Birds independently developed endothermy and four-chambered heart working at rates compared to those or higher than that in mammalians. However, the morphology of their cardiomyocytes is close to that in reptiles. To figure out how birds have solved this contradiction between the structure and the function, we have for the first time studied the interplay between sarcolemmal calcium flux and Ca2+-dependent Ca2+ release from sarcoplasmic reticulum in isolated avian cardiomyocytes. Our results have shown that Ca2+ cycling in avian myocardium strikingly differs from that in mammalians - and yet, it provides the high efficiency of the bird heart.
10-07-2020 15:00 - 15:15
Hosted by: Tatiana FilatovaMessages will be visible for table members and will NOT be shared on Facebook.